## Deciding on an immunohistochemical panel
Transcription factors tend to be very highly expressed, even in poorly differentiated tumors. Examples include:
* SATB2 (esp. in lower GI mucosal/NET, cutaneous NET, bone, and *BCOR*-rearranged sarcomas)
* GATA-3 (breast)
## Stains to determine oncologic treatment
* SCC:
* PD-L1
* Lymphoma:
* CD45, CD43 (R-CHOP)
* Melanoma
* SOX10 (Anti-BRAF, checkpoint inhibitors)